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J Transl Med 18:100 Lin T-N, Cheung W-M, Wu J-S, Chen J-J, Lin H, Chen J-J, Liou J-Y, Shyue S-K, Wu KK (2006) 15d-prostaglandin J2 protects brain from ischemia-reperfusion injury

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Notably, 1 O exihibits a high degree of chemical reactivity, allowing it to directly target lipids, proteins, and DNA in cell membranes, thereby inducing oxidative damage [88]

Originally approved for type 2 diabetes management in May 2022 and later for chronic weight management in November 2023, tirzepatide was never designed with autoimmune conditions in mind