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These markers help quantify the metabolic benefits of tirzepatide beyond weight loss

Additionally, patients with inflammatory bowel disease, severe gastroesophageal reflux disease, or other significant gastrointestinal disorders should be monitored closely if treatment is initiated, as the gastrointestinal effects of semaglutide may worsen their underlying condition

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The authors point out, therefore, the potential benefit of reducing the burden of Pb in the exposed populations (Table 2)

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