Recently, it has been illustrated that HCBP6 (FUNDC2), a mitochondrial outer membrane protein FUN14 structural domain containing 2, can interact with and destabilize SLC25A11, thereby affecting mGSH levels and regulating ferroptosis in the myocardium [61]
The upregulation of these genes suggests improve pancreatic -cell function, leading to enhanced insulin production and secretion (120)
Glutathione is a naturally occurring antioxidant produced by the body, with particularly high concentrations in the liver, where it plays a vital role in detoxification and protecting cells from damage
doi: 10.2174/0929867327999200716112353 64
Applications Applications Glutathione & thioredoxin reductase inhibitor Functions Functions Inhibits glutathione reductase and thioredoxin reductase, IC50s=6.7 and 8.7 M respectively, and impairs mitochondrial function
Methylglyoxal detoxification revisited: Role of glutathione transferase in model cyanobacterium Synechocystis sp