Br Med J (1950) 2(4685):9058.10.1136/bmj.2.4685.908 7 LederleFA
Signs to look out for include fatigue and lethargy, depression, irritability, headaches, difficulty with balance, decreased cognitive function, constipation, sore or swollen tongue, heart palpitations, mouth ulcers, pins and needles and changes to vision
However, vitamin C injections are typically only used when vitamin C levels need to be increased quickly or when oral supplements cant be taken due to poor absorption or other reasons
Improvement in quality of life after surgery for glomus tumors of the fingers
Most healthy individuals tolerate these supplements very well, and there is no evidence that excess vitamin B12 causes harm because unused amounts are excreted by the body
Specific compatibility considerations include confirmation of absence of reducing agents for disulphide-containing peptides, BSA carrier supplementation for recombinant proteins, and acetic acid acidification for hydrophobic peptides requiring low pH solubilisation
