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doi: 10.1016/j.lfs.2017.12.015

The scientists suggested that there may have been a correlated increase in the animals body weight and BMC, as measured by dual X-ray absorptiometry (DXA)

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Non-canonical pyroptosis is initiated by the detection of intracellular lipopolysaccharide (LPS) from Gram-negative bacteria, leading to the activation of caspase 4 (CASP4) and caspase 5 (CASP5) in humans and caspase 11 (CASP11) in mice, which cleave GSDMD independently of inflammasome assembly

However, that doesnt mean Cinderella IV is weaker. In fact, it often plays a supportive role