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2.17 TUNEL Cell or tissue sections were fixed with 4% paraformaldehyde at room temperature for 15 min, followed by three washes with phosphate-buffered saline (PBS)

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Elevated histone acetylation was confirmed in an additional cell line and shown to decrease through the depletion of KG or the suppression of KGDDs using knockdown or inhibition of IDH1, glutamine starvation or succinate supplementation (Fig