Summary Vitamin B 12 or cobalamin plays essential roles in folate metabolism and in the synthesis of the citric acid cycle intermediate, succinyl-CoA
And in the 80s it increased to every three months, which is still what they use today
I had this extreme tiredness when I first started B12 injections
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Nearly five months after my initial panic in May, my symptoms have virtually disappeared
Some historical or research protocols have used much higher doses (e.g., 250 mg/kg as a single IV bolus in diagnostic growth-hormone testing), but such regimens are uncommon outside controlled studies.Dose escalation should proceed cautiously, with monitoring of vital signs, electrolytes, and-if relevant-ammonia levels
