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This model is especially common in chronic pain management, where medications are often used repeatedly over time without correcting the underlying cause

Nutritionists work personally with each patient and use their own algorithm to craft meal and snack plans that are compatible with each patients age, gender, activity level, food preferences, nutritional needs and medical conditions

Default settings were applied for all other parameters

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doi: 10.1007/s12178-025-09990-7

rather, its activity is mediated through modulation of multiple intersecting pathways