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Consequently, direct investigations within AD models and patient cohorts are essential to validate the precise mechanistic role of DNA methylation in regulating ferroptosis during neurodegeneration

The molecule cycles between its reduced (GSH) and oxidized (GSSG) forms, donating electrons to neutralize reactive oxygen species (ROS) either directly or through glutathione peroxidase-catalyzed reactions

First identified in 1973 by researcher Loren Pickart, this peptide is naturally present in human plasma, saliva, and urine

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doi: 10.1016/j.freeradbiomed.2022.12.105 18

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