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Analogue 1.62 Compound 1.62 was extensively characterised, and its structural and chemical properties were confirmed

For example, using 16S rDNA sequencing technology, it has been demonstrated that children with Chlamydia pneumoniae exhibit impaired intestinal flora diversity and a marked reduction in Bifidobacterium abundance

GSH is composed of glutamate, cysteine, and glycine and is synthesized intracellularly via two reactions catalyzed by -glutamylcysteine ligase (GCL) and GSH synthetase (GS) [5,6]

MIC of combined agents was determined and compared with the MIC of antibiotics alone

Conventional oral glutathione is broken down into its constituent amino acids before reaching the bloodstream, delivering negligible intracellular GSH elevation

For GSEA analyses, the fgsea package was used 132