Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71
"Pharmaceutical Development of Long-Acting Peptide Therapeutics: Technical Considerations and Market Opportunities." Drug Discovery Today, 28(3), 103491
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Safety and tolerability of putaminal AADC gene therapy for Parkinson disease
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