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In the response to a high-fat diet and free fatty acids, the level of frataxin in the liver is significantly reduced

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[58] have shown that Nrf2 deficiency leads to oxidative stress and DNA lesions, accompanied by impairment of cell-cycle progression, mainly G(2)/M-phase arrest

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If supplementing is the next step for you, you need to consider which form of B12 is the right choice for your symptom picture