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An orange peel extract in which HD is the main compound can protect rat liver from CCl4-induced injury by lowering the levels of AST and ALT, and by increasing the content of glutathione, the activities of SOD and glutathione peroxidase ( 2.5.1.2 Effects of HD on hepatic lipid metabolism HD has been reported to have a therapeutic effect on lipid disorders in the liver

These reactions can be worse when glutathione is given through IV

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It can also be given as an IV bag at higher dosages and the cost is $110