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Together, these results support the possibility that peripheral immune-metabolic alterations are linked to neurodevelopmental pathways implicated in ASD, consistent with emerging evidence that immune signaling can influence brain development

We herein consolidate the research paradigm, historical advances, and future trajectories concerning lactate metabolism and Kla in TME-mediated immune suppression

10.1081/CLT-100102388 Watson WA, Litovitz TL, Klein-Schwartz W, Rodgers GC Jr, Youniss J, Reid N, Rouse WG, Rembert RS, Borys D: 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System

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88: 142-149 (2025) Ostergaard S, Olsson L, Nielsen J