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These smart agents minimize off-target toxicity while maximizing reactive oxygen species production at disease sites, thereby enhancing therapeutic efficacy and safety [74]

The RNA-seq and qRT-PCR results for both up- and downregulated genes showed a strong positive association (r = 0.854, p = 0.007

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Further, the diselenide block copolymer as drug carrier has been demonstrated, which can be cleaved and oxidized into selenic acid in oxidative environment, whereas, reduced into selenol in the reducing condition

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