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AOD-9604 is an intellectually interesting compound whose mechanism is well-characterized in preclinical models, whose safety profile is genuinely clean, and whose clinical program ultimately did not deliver

One note:alcohol consumption can drastically deplete B vitamins (especially thiamine and folate)

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Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme essential for cellular energy production and DNA repair

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Nicotinamide N-Methyltransferase (NNMT): A New Hope for Treating Aging and Age-Related Conditions