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Beyond CPPs, other functional peptides have also been exploited for PNA delivery

(Silver Spring) 29 , 350358 (2021)

Polyphenols are good reducing agents, but, according to this authors thesis, they also have the potential to act as pro-oxidants

Legal status (US): Neither TB-500 nor thymosin beta-4 is FDA-approved for any human indication

The peptide increases expression in 59% of affected genes while suppressing 41%, essentially resetting pathological gene patterns back to healthier states

India Research in animal models using both peptides is anticipated to reveal enhanced benefits without dramatically increasing adverse effects