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Synthesis, biological evaluation and molecular modeling study of 2-(1, 3, 4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors

Under physiological conditions, NO is involved in processes such as neurotransmission, blood pressure regulation, defense mechanisms against pathogens, and immune response regulation [2]

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