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after a second administration one week later, this parameter reached 10.8%, with an editing frequency of 21% in isolated hepatocytes
The COCs were then homogeneously distributed in 4-well plates with 500 L of maturation medium: TCM199 and 4 L/mL gentamicin, 100 M cysteamine, 10 g/mL follicle-stimulating hormone (FSH), 10 g/mL luteinizing hormone (LH), and 10% fetal calf serum (FCS)
However, mechanistic studies of redox imbalance remain challenging due to limited strategies that can perturb redox metabolism in various cellular or organismal backgrounds
