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Stem Cells Translational Medicine

10.1073/pnas.90.1.50 Proc

Upon IB degradation, NF-B is released and translocates into the nucleus, where it recruits p300, which in complex with cAMP response element-binding protein acetylates RelA/p65, thereby activating NF-B transcription and enhancing the expression of downstream pro-inflammatory genes (Lawrence 2009)

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The Key Role of Mitochondrial Function in Health and Disease