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By binding to Toll-like receptor 4 (TLR4) on HSCs and KCs, it activates the NF-B signaling pathway, promoting the expression of inflammatory factors and fibrogenic factors, thereby exacerbating hepatic inflammation and fibrosis (Reid et al., 2016)

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5-Amino-1MQ, also known as 5-amino-1-methylquinolinium, supplied as a 10mg lyophilised research material

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The blood communicates with all other tissues none of which are in our model