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In addition, a case-control study ( n = 257 cases, 133 controls) in 1993 reported that lower riboflavin intake, assessed via 24 h dietary recall, was associated with increased risk of cervical intraepithelial dysplasia, an early stage proceeding invasive cervical cancer 139

Their proposed mechanisms of action include the promotion of angiogenesis, modulation of inflammatory cascades, and enhancement of tissue repair through multiple cellular pathways

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Sequences from taxa other than bacteria were served as a performance control, ensuring that the 16S rRNA sequencing reads would not identify viral hits