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Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes

Clinical research involving approximately 900 participants across six human trials specifically measured serum IGF-1 concentrations and found no changes with AOD-9604 treatment at doses up to 1 mg per day and beyond

Baseline: CBC, B12, folate, iron studies Repeat B12 levels 1 month after loading dose Annual checks for chronic therapy Monitor potassium during initial treatment Neurological exams for neuropathic symptoms B12 injections can "mask" megaloblastic anemia from folate deficiency while allowing neurological damage to progress

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doi: 10.1002/cbf.1631 59 ReschUHelselGTatzberFSinzingerH

The genetics of gout: towards personalised medicine