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Pregnant women aged 18 y who presented for prenatal care before or at 14 wk of gestational age (as judged by the date of the last menstrual period) were eligible for inclusion

The University of Michigan also warns that a B12 shot is not recommended for people with Lebers disease (7)

Your practitioner will review your symptoms, medical history, and any relevant test results before recommending an appropriate treatment protocol

Hence, how often do you obtain B12 injections for weight loss

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This means shots are almost 100% effective