Riboflavin (B2): Aids in energy production, metabolic processes, and supports antioxidant function
Cerebrolysin has been investigated extensively in preclinical and clinical research literature for neurotrophic-like activity, with proposed mechanisms involving CNTF-domain and IGF-1-domain peptide fragments, BDNF expression endpoints, and mitochondrial function research in neuronal cell models
PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 62 H 98 N 16 O 22 Weight: 1,419.53 g/mol CAS: 137525-51-0 Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily dissolves in water Stability: Stable across various pH conditions Storage: Keep refrigerated 3646 F (28 C)
Safety Profile Generally safe and suitable for sensitive skin
The results of a randomized clinical trial revealed that the efficacy of thiamidol cream 0.2% was comparable with hydroquinone cream 4% (Vachiramon et al., 2021)
Normalization of data to an internal standard was performed using an in-house R script, then values were normalized to protein content per treatment condition