Research has shown that long-term use of certain drugs can interfere with absorption pathways
for 4 weeks, has also shown benefit alongside pregabalin (a drug commonly used for neuropathic pain), but as this was an uncontrolled trial the contribution B12 made to the improvements cannot be established
The liver can store the vitamin for a long time, so it may take a few years for deficiency and symptoms to develop
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The manufacturing of vitamin b1, b6, and b12 injection requires sophisticated and highly aseptic equipment for each step from production till packaging
Patients should inspect the expiration date upon receiving their medication from the pharmacy and organize their refrigerator storage to use medications with earlier expiration dates first