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For example, a study employing tandem ubiquitin-binding entity (TUBE) proteomics analyzed ubiquitination profiles in HEK293T cells exposed to five types of cellular stressheat shock, oxidative stress, osmotic stress, UV irradiation, and proteasome inhibition

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The sensitivity of the forward rate constants for the superoxide formation reaction, k p2 , and the oxygen concentration parameter, k O2 , proved to be the most sensitive globally with respect to total effects, highlighted in Fig

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doi:10.1006/bbrc.2000.2800