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Urate promotes SNCA/-synuclein clearance via regulating mTOR-dependent macroautophagy

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Fear of needles, concerns about sterile technique, discomfort, and the psychological barrier of self-injection all limit adoption of injectable peptides

However, larger trials have not consistently shown mortality benefit (Rank et al., Crit Care Med, 2000) [41]

These results suggest an association between metformin-induced enhancement of intestinal glucose uptake and excretion, and TXNIP-mediated regulation of intestinal GLUT1 in diabetic mice

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