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Four molecule families have peer-reviewed clinical evidence supporting their use in microinfusion-style delivery: copper tripeptide GHK-Cu (collagen synthesis, gene-expression modulation), recombinant epidermal growth factor or sh-Oligopeptide-1 (keratinocyte proliferation, dermal restructuring), polydeoxyribonucleotide PDRN (adenosine A2A receptor activation, fibroblast stimulation, anti-melanogenesis), and a multi-molecular-weight hyaluronic acid system (50 kDa to 2000 kDa fractions, each with different penetration depth and biological role)

Morgan AS, Sanderson PE, Borch RF, Tew KD, Niktsu Y, Takayana T, VonHoff DD, Izbicka E, Mangold G, Paul C, Broberg U, Mannervik B, Henner DW and Kauvar LM

Fruit and vegetables and cancer risk

Hessling, B

PLoS ONE 13 , e0209340 (2018)

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