Psychopharmacology 207:257270 Wu K-J, Hsieh M-T, Wu C-R, Wood WG, Chen Y-F (2012) Green tea extract ameliorates learning and memory deficits in ischemic rats via its active component polyphenol epigallocatechin-3-gallate by modulation of oxidative stress and neuroinflammation
Balancing angiogenesis: Critical distinction between therapeutic angiogenesis (restoring blood flow to ischemic areas) versus pathological neovascularization (abnormal vessel growth in wet AMD or proliferative diabetic retinopathy)
DAC stands for Drug Affinity Complex , a molecular structure added to a peptide to prolong its half-life
We used structural modeling and biophysical tools to confirm exactly how the peptide binds and blocks the interaction
Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J
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