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Numerous curcumin derivatives have been synthesized over the last two decades to develop molecules with enhanced antioxidant activity

However, this popularity has often outpaced the actual clinical evidence, creating a significant gap between laboratory enthusiasm and evidence-based claims about human application

In animal studies, the impact of DSIP has been shown to mitigate stress-related changes in GABA, glutamate, aspartate, and lipid peroxidation, highlighting its potential to alleviate anxiety (4)

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Therefore, anti-angiogenesis therapy can be used to reverse drug resistance in breast cancer 7