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Be sure that you only leave the patch on for 8 hours as stated in the caution statement

Avoid repeated freeze-thaw cycles, which may compromise compound integrity

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[13] Additionally, the benefits demonstrated the reduction in visceral abdominal fat that remained for upwards of 52 weeks according to a double-blind placebo clinical trial

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By inhibiting NNMT, 5-Amino-1MQ may spare nicotinamide for NAD+ synthesis, thereby activating SIRT1 (Sirtuin 1) pathways associated with mitochondrial biogenesis and fat oxidation [3]