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The following experimental examples show changes in each aforementioned index as a consequence of erastin stimulation

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It is theorized that this process could involve the activation of the PI3K-Akt and JAK2-STAT5 pathways (pathways with essential roles in cell growth, survival, and metabolism), along with a reduction in NF-B-mediated gene transcription (proinflammatory pathways that can lead to cell damage and death)

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