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Hence, a peptide was designed by substituting the negatively charged residues D42, D48, D49, E51, E56, and D57 within the p53 TAD PEP with alanine to increase its binding affinity to FOXO4 FHD and enhance membrane penetration

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The neurotransmitter glutamate has two major ionotropic receptors (NMDA and AMPA/kainate receptors), which are widespread in the cerebral cortex and other brain regions

Strong acids, retinoids, and vitamin C may interact with or destabilize GHK-Cu when applied simultaneously

Switch to intravenous (IV) or nebulized glutathione if medically appropriate

Protein Misfolding and Cellular Stress in Disease and Aging