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Certain organ diseases and especially tumors are associated with the occurrence of this pathological manifestation

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This approach, which often involves applying a fraction of the standard dose, is designed to investigate the cellular or physiological responses without provoking the full-blown effects of the drug

The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007