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Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

NNMT stands for nicotinamide N-methyltransferase , an enzyme involved in cellular metabolism

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In most food sources, B12 is bound to a protein molecule released by the metabolic activity of hydrochloric acid and other enzymes in the stomach

Its naturally available from animal products, including fish, meat, poultry, eggs, milk, and milk products but its not usually present in plant foods

PMID: 41093057 Adv Sci (Weinh) The GLP1R Agonist Semaglutide Inhibits Reactive Astrocytes and Enhances the Efficacy of Neural Stem Cell Transplantation Therapy in Parkinson's Disease Mice