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It can increase heart rate and blood pressure, which means it is generally contraindicated for patients with a history of heart disease, hyperthyroidism, or uncontrolled high blood pressure

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Similarly, melatonin was used as an adjuvant for the prevention of POF during chemotherapy (184, 185), given its experimentally proven role in the female reproductive tract (186)

Medial Tibial Stress Syndrome (MTSS), commonly known as shin splints, is a painful condition that affects the front or inner part of your lower leg along the shinbone (tibia)

If it doesnt, the symptom probably has another cause

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