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Approximately 11.9-fold increase in endogenous MOTS-c levels have been found in skeletal muscle following exercise (compared to pre-exercise values), and this increase can remain for 4 hours following exercise (19)

Thus, higher PM 2.5 was associated with lower SRS scores through the direct effect of prenatal PM 2.5 exposure on the SRS scores and through the indirect effect of prenatal PM 2.5 exposure on SRS scores through its effect on respiratory parameters associated with ATP production

Most true peptides are not orally bioavailable because stomach acid and digestive enzymes break down amino acid chains before they reach systemic circulation

Co-immunoprecipitation studies demonstrated that the peptide reduces eNOS/caveolin-1 binding by approximately 50%, effectively doubling the available eNOS for nitric oxide production