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Physical exercise, particularly aerobic and resistance training, modulates both systemic and neural inflammation, potentially supporting cognition by reducing cytokine levels and enhancing neuroimmune balance (41)

Differential Diagnosis Inherited hemolytic anemias: Other enzyme deficiencies (e.g., pyruvate kinase Pyruvate kinase Atp:pyruvate 2-o-phosphotransferase

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Biochim Biophys Acta Bioenerg

This regulation of SIRT2 could contribute to myelination and neuronal differentiation, supporting retinal cytoarchitecture maturation