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FiO2, Fraction of inspired oxygen
The arginine substitution at position 3 and the N-terminal extension collectively reduce IGFBP affinity by approximately 1001,000-fold in preclinical binding assays
Identification of caspase-8 as a cell fate-regulating enzyme in mature erythrocytes might have far-reaching implications for RBC biology, since the ability to regulate and select cell death modalities questions a conceptual view on erythrocytes as entities existing in a state between life and death
2.8 GPX8 Glutathione peroxidase 8 (GPX8) is a type II transmembrane protein with rare structural features that consists of 209 amino acids (Yoboue et al., 2017)