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Less infiltration of immune cells and absence of hemorrhages was observed in the bladder tissue of extract treated group, showing anti-inflammatory activity of the H

doi: 10.3390/ijms241310770 155 ShiJZhaoYWangKShiXWangYHuangHet al

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Malabsorption of folate and vitamin B 12 has been reported in non-pregnant individuals and older adults with hypochlorhydria and atrophic gastritis in different studies (Reference Russell, Krasinski and Samloff35,Reference Carmel36)

Finally, the impact of ADPKD-related systemic abnormalities (e.g., electrolyte disturbances, hypertension, and liver cysts) on ferroptosis pathways and therapeutic responses is unexplored, which may affect the translatability of preclinical findings