Real-world testing bears this out, with retinoid content in some products dropping anywhere from 0% to 80% after six months at room temperature, and even more at higher temperatures
While this can be beneficial for people with mood disorders, such as depression, it can sometimes do the opposite of what was intended, and lead to restlessness, anxiety, trouble sleeping, and worry
Expert advice Free radicals are oxidizing agents produced by oxygen-using processes, particularly respiration
Additional oral or sublingual B12 supplementation is generally safe alongside the blend, though likely unnecessary for most patients since the injection provides direct B12 delivery
Price Comparison This dupe is $8.49 more expensive than the original product
It is worth noting that much of the community discussion assumes a single pre-mixed vial as the default starting point