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112 Upon reaching the liver, bacterial extracellular vesicles function as highly targeted delivery vehicles, independently unloading concentrated packages of virulence factors, microbial small RNAs, and active metabolites directly into hepatic non-parenchymal cells
compared to WT controls
doi:10.1021/jf071957p 165
Watkins et al.[38] studied the effect of chronic APAP ingestion (using the same protocol of 1000 mg every 6 hours for 14 days) on liver damage as measured by elevation of serum alanine aminotransferase (ALT)