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ALOX12, Arachidonic acid 12 lipoxygenases

doi: 10.1016/0140-6736(93)90006-3

(2024) Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism Able, C

Ang II binds to hepatic AT1 receptors, triggering NADPH oxidase 4 (NOX4)-dependent ROS production, which activates the NLRP3 inflammasome, promotes caspase-1 activation and IL-1 release, and ultimately induces hepatocyte pyroptosis [26, 38]