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demonstrated that although both of them metabolized 3-methylindole via either epoxidation or dehydrogenation pathways, CYP2F2 was favorable to produce reactive iminium ions while CYP2A5 was favorable to produce stable derivatives, which caused different degrees of injury to mouse (Zhou et al., 2012)

The injection should be given by a qualified healthcare professional, such as a doctor or nurse

In addition, the same authors also identified a panel of FDA-approved drugs for their ability to inhibit globally or individually all GPX proteins or only specific ones [50]

In over 90% of individuals with cEDS a dominant pathogenic variant in either COL5A1 or COL5A2 is identified