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The researchers discovered that glutamine metabolism is impaired in the obese state, leading to increased chromatin O-GlcNAcylation and activation of genes in proinflammatory pathways

Rouhier N, Lemaire SD, Jacquot JP (2008)

But for some time now, like many food supplements, it has been the subject of much controversy and its effectiveness has been called into question

Injectable products require separate sterility, endotoxin and particulate testing

Cravings, particularly for high-calorie processed foods, diminish substantially

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