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Cognitive and physical lifestyle factors may also be influential, given that sedentary behaviour is associated with an earlier onset and greater severity of symptoms [142]

ANOVA with Brown-Forsythe post-hoc test for multiple comparisons was performed to determine statistical significance (*** P = 0.0007)

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This relationship is evident in conditions like rheumatoid arthritis, inflammatory bowel disease, and lupus, where oxidative stress contributes to inflammation and tissue damage