If you do notice any reaction at the injection site (such as warmth or a small lump), it can help to gently apply a cool compress
Caution is warranted because animal findings do not reliably map onto what happens in people
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Do not chew, crush, or split the tablets, as this may damage the tablet structure and affect drug absorption
Many of the FDA advisers and internal staff who oversaw those decisions no longer work for the agency
That system can break down if you: Take acid blockers (PPIs like omeprazole) or antacids regularly Have low stomach acid from age or chronic stress Have had GI surgery (gastric bypass, bowel resection) Live with conditions like celiac, Crohns disease, or IBS Have autoimmune pernicious anemia Even with high-dose tablets (e.g., 1000 mcg), only a small fraction may reach your bloodstream