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The downstream pathways mediated by ACSL4 (acyl-CoA synthetase long chain family member 4) result in the production of different PUFA-related acyl-CoA esters [85,86,87] (Fig

Godex markedly reduced fasting blood glucose and insulin resistance indices while enhancing insulin sensitivity in NAFLD mice (33)

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The cancer cells that survive IRE treatment, or those targeted by nsPEF, can subsequently undergo death via pathways such as apoptosis ( Fundamental studies indicate that high-intensity electric pulses can significantly increase cell membrane permeability