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FOXO4-DRI vs Other Senolytics FOXO4-DRI is one of several approaches to clearing senescent cells, and they are not interchangeable

doi: 10.1111/j.1365-2249.2006.03271.x 165 VenkenKHellingsNThewissenMSomersVHensenKRummensJ-Let al

This research described MOTS-c as a mitochondrial-derived peptide that regulates insulin sensitivity and metabolic homeostasis

The depletion of this antioxidant has been correlated with lower immune function and increased vulnerability to infection due to the liver's reduced ability to detoxify

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10.1016/j.bbcan.2019.188314 6 BaiJ.ZhangY.TangC.HouY.AiX.ChenX.et al (2021)